Preheat the oven to 375 degrees. Prepare a sheet pan by spraying it with cooking spray.
Mix flour and Greek yogurt together using a mixer with a dough hook. Start on slow and then increase the speed as dough starts to form. You may need to scrape down the sides to get all the flour incorporated. Keep mixing until it forms a soft, sticky dough. Note: If you don't have a mixer, you could also mix the flour and yogurt together until combined. Then flour a surface and knead the dough until a dough forms. Continue kneading for a few minutes. You may need to add additional flour if dough is too sticky to work with. Lay out a sheet of wax paper for easy clean up. Spray your hands with cooking spray and then divide the dough into 12 equal portions. Mine were around 47 g. Once dough is evenly divided, spray your hands with cooking spray again and roll the dough between your hands to create a rope shape, about 7 inches long. Once long enough, create a knot with the dough and tuck the edges in. Place completed knot on the prepared baking sheet. Repeat with remaining portions of dough. You may need several sprays of cooking spray on your hands. This dough is sticky!
In a small bowl, combine the melted butter, Parmesan, garlic powder, oregano, parsley, and salt. Evenly spread the mixture over the prepared knots.
Bake the knots for about 20- 25minutes, or until the tops are golden brown. Remove from the oven and enjoy! Best served warm!